Stochastic analysis of biochemical reaction networks with absolute concentration robustness

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Stochastic analysis of biochemical reaction networks with absolute concentration robustness.

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' (ACR) on a wide class of biologically relevant, deterministically modelled mass-action systems. We show here that fundamentally different conclusions about the long-term behaviour of such systems are reached ...

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Supporting Online Material for: Stochastic analysis of biochemical reaction networks with absolute concentration robustness

2 Background, terminology, and notation 2 2.1 Chemical reaction networks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2 Deterministic chemical reaction systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.2.1 Absolute concentration robustness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.2.2 Reformulation of equ...

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ژورنال

عنوان ژورنال: Journal of The Royal Society Interface

سال: 2014

ISSN: 1742-5689,1742-5662

DOI: 10.1098/rsif.2013.0943